Anatomical and experimental studies show that the superficial fascia – the soft tissue layer we contact with light myofascial strokes – contains dense lymphatic networks and plays an important role in fluid balance. Recent animal research also suggests that gentle mechanical stimulation over the face and neck can enhance cerebrospinal fluid drainage via lymphatic vessels.
While these findings are early-stage and mostly pre-clinical, they support the rationale for using light, fascia-focused techniques to support fluid movement and comfort around the head and neck.”
Key references
Jin H et al., 2025 – Nature
Nature
Increased CSF drainage by non-invasive manipulation of cervical lymphatics
In mice, a force-regulated device applying light, repeated strokes over the facial and cervical skin (above superficial lymphatics) doubled CSF outflow and partially restored impaired brain-waste clearance in aged animals, showing that gentle mechanical stimulation at the skin/fascia level can up-regulate CSF–lymph drainage.
Wang W et al., 2025 – Translational Neurodegeneration
SpringerLink
Harnessing cervical lymphatic mechanics to enhance amyloid clearance
Commentary on Jin et al.: describes how mechanical manipulation of superficial cervical lymphatics boosted CSF drainage and amyloid-β clearance in animal models, and discusses potential translation to non-invasive human therapies.
Albertin G et al., 2023 – Life
MDPI
Detection of Lymphatic Vessels in the Superficial Fascia of the Abdomen
Anatomical study showing that the superficial fascia contains a rich, dense network of lymphatic vessels, with higher vessel density and calibre than adjacent layers – supporting the idea that fascial layers are key pathways for lymph transport and that gentle fascial work overlies a major lymph network.
Fede C et al., 2025 – The Human Superficial Fascia: A Narrative Review (Int. J. Mol. Sci.)
MDPI
Reviews the superficial fascia as a distinct anatomical layer involved in lymphatic flow and venous circulation, highlighting its role in fluid balance, immune function and tissue sliding throughout the body (including head and neck).
Stecco A et al., 2016 – PM&R
ScienceDirect
+2
Wiley Online Library
+2 Fascial Disorders: Implications for Treatment Narrative review linking fascial stiffness and dysfunction to pain and movement issues. It discusses pre-lymphatic structures, superficial fascia and the lymphatic system, and notes that effective fascial treatments can often be achieved with light massage or broad-surface techniques, not just deep pressure.
Ajimsha MS et al., 2015 – Journal of Bodywork & Movement Therapies
ScienceDirect
Effectiveness of myofascial release: Systematic review of RCTs
Summarises RCTs where myofascial release (MFR) improved pain and range of motion. Mechanistically, it notes that MFR directs force to fascial fibroblasts and indirectly strains nerves, blood vessels and the lymphatic system, supporting a role for fascial techniques in influencing fluid and tissue physiology.
Schleip R, 2021 – “Water and Fluid Dynamics in Fascia” (chapter excerpted in Fascia Insights)
novo.pedroprado.com.br
+2
FASCIA RESEARCH PROJECT
+2
Reviews fascia as a major water-rich tissue (≈ 68% fluid) and describes how manual pressure, shearing and movement temporarily alter water content and fluid distribution within fascial tissues – a plausible mechanism by which gentle myofascial strokes can support interstitial and lymphatic fluid movement.
Fasciaguide summary – “Fluid flow in the fascia & how it is affected by treatment and vibrations”
The Fascia Guide
+1
Collates experimental work showing that manual therapy and low-level vibration increase fluid flow in connective tissues, tying together fascia, hydration and mechanical loading.
